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For hematocrit and reticulocyte counts, recommendations are to repeat these tests daily from the 5th to 7th days of treatment and then frequently until the hematocrit returns to a normal range.[9][16][22] Both serum potassium concentrations and the platelet count need to be monitored carefully after parenteral administration of cyanocobalamin

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The RPMI Basal Medium was composed of RPMI-1640 HEPES medium, 1X B-27 Supplement with insulin, 1X Minimum Essential Medium non-essential amino acids solution (NEAA) and 1X penicillin/streptomycin (PEST) (all from Thermo Fisher Scientific, Inc.)

Anaphylaxis: Rare cases of anaphylaxis have been reported following injection