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51 New Therapeutic Agents The development of novel therapeutic agents is a challenge, mainly because of the difficulty in designing clinical trials to study the effects of drugs on AD progression, since clinical benefits must be demonstrated in terms of cognitive performance

Additionally, toll-like receptor 4 (TLR4) can induce necroptosis via interaction between the toll receptor-associated activator of interferon (TRIF) and the necrosome (Solon et al., 2024)

Nature 47:523526 Salinas AE, Wong MG (1999) Glutathione S -transferases a review

Kenya has sought to include all other armed groups in government but Uganda has always wanted to limit the role of Machar, and elevate Kiirs powers, a government official in Nairobi explained