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Glutathione is a tightly regulated intracellular constituent, and is limited in its production by negative feedback inhibition of its own synthesis through the enzyme gamma-glutamylcysteine synthetase, thus greatly minimizing any possibility of overdosage

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(2024) Evaluating the impact of testosterone replacement therapy on carotid atherosclerosis: a systematic review and meta-analysis Sigalos JT, Pastuszak AW