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Trends Food Sci Tech 50(4):103117
If this finely tuned balance in BH4 concentration is perturbed, several biological systems are compromised, resulting in impaired neurotransmission, immune responses, metabolism, and vascular activity (Figure 5)
Discovery of GSK2795039, a novel small molecule NADPH oxidase 2 inhibitor
Variation in redox state, as represented by the intracellular GSH:GSSG ratio, can have profound clinical implications, enhancing cell signalling and even cell death
