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53 Although dementia was not a primary outcome, a pooled analysis of 15,820 patients with type 2 diabetes randomised to GLP-1 receptor agonist treatment or placebo found a 50% reduction in dementia progression over a median of 3.6 years (15 cases in the placebo group vs 32 in the GLP-1 receptor agonist group)

The safety of chronic usewhich would be required for preventionis uncharacterized

After seeing how great they feel, many patients choose the convenience and savings of doing injections at home

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ICH stability guidance calls for monitoring appearance, visible particles after reconstitution, pH, and other quality attributes