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Approximately 50% of AD patients exhibit alpha-synuclein pathology, while up to 50% of PD patients with dementia have amyloid-beta proteins and neurofibrillary tangles that are sufficient enough for secondary AD diagnosis (Irwin et al., 2013

Deionized water provided by the Milli-Q water purification system was used for the entire experiment

qPCR was then performed using Power SYBR Green PCR Master Mix (Applied 509 Biosystems) in StepOnePlusTM Real-Time PCR Systems using respective qPCR gene specific primers

doi: 10.1016/J.METABOL.2020.154304 35 NatalicchioALabarbutaRTortosaFBiondiGMarranoNPeschecheraAet al