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J Thorac Cardiovasc Surg 158(2):630-631, 2019

Jadhav- [[email protected]](mailto:[email protected])) on reasonable request

Fumarate binds with antioxidant glutathione to produce succinated glutathione (GSF), which is an alternative substrate to glutathione reductase (GR) and downregulates NADPH levels while promoting ROS production [30]

However, transcript levels of the cytosolic SOD-5 in ctl-2(ua90)II strain were increased 15-fold already at OGT compared with WT and were comparable to WT HS levels (Fig 2C)