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All supplements may carry a risk of causing negative health effects, and safe dosages will depend on individual factors

Selenium deficiency impairs the glutathione antioxidant system even when glutathione levels are adequate [26]

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Additionally, mRNA expression of iron response element binding protein 2, encodes a master regulator of iron metabolism), and CS (citrate synthase, regulating the mitochondrial fatty acid metabolism) was upregulated in both models, while ACSF2 ((acyl-CoA synthetase family member 2, regulating the mitochondrial fatty acid metabolism) was upregulated only in APPswe/PS1dE9 mice