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In normal cases, PINK1 is degraded by healthy mitochondria, but when mitochondria become dysfunctional or damaged, PINK1 accumulates on their outer membranes, recruiting Parkin to mark the defective organelles for autophagic degradation

AK: Data curation, Formal analysis, Investigation, Methodology, Resources, Writing original draft

Brief first-week fatigue Community reports cluster around a 1-3 day fatigue window in the first week, sometimes attributed to metabolic shift

doi: 10.3390/ijms24043594