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(2/)ROS-targeting therapies were tested

We would like to thank the students from the Department of Communication, Lauren Archibald '18, Brian Lloyd '18 and Daniel Valentino '17, along with their professor John Kilker, III for the production of this video

4.4.1 Glutamine Glutamine metabolism not only promotes the synthesis of succinic acid by fueling the TCA cycle in M1-type macrophages, but also drives M2 polarization via the conversion to glutamate and then -KG, with high -KG levels and a high -KG/succinate ratio facilitating macrophage reprogramming towards the M2 phenotype (Liu et al., 2017)