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This evidence was strengthened by studies in vivo in which manipulation of calpastatin levels, an endogenous calpain inhibitor, led to modulation of the neurological phenotype seen in a SCA3 mouse model, as well as of mutant ATXN3 aggregation and neurodegeneration, consistent with a role for calpain activation in pathogenesis [50, 52]

doi: 10.3390/molecules25010182 9

Anthocyanidins and cyanidin-3-glucoside (C3G) found in bilberry have been shown in preclinical studies to protect eye health

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a) Al corte histolgico, neoplasia maligna pleomorfa de grado alto