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For example, people who are experiencing loss of kidney function due to diabetes may find that high strength B12 supplementation can cause the loss of function to speed up (House et al., 2010), and high dose supplements of B12 may also increase the risk of colon cancer in older people

B12 deficiency and hair loss: Stronger evidence

Moreover, both inhibited CD38 cyclase activity

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Some key health conditions associated with these symptoms include: Liver Disease: In conditions like hepatitis, fatty liver disease, or liver cirrhosis, damaged liver cells may release excess B12 into the bloodstream, causing elevated levels 7 , 17