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[DOI] [PubMed] [Google Scholar] 668.Kettle AJ, van Dalen CJ, Winterbourn CC

Nat Biotechnol 29: 449-452

10.1007/s12291-014-0446-0 78 PiettaP

Lymphatic delivery and pharmacokinetics of methotrexate after intramuscular injection of differently charged liposome-entrapped methotrexate to rats

As highlighted by Adegbola, the gut microbiome plays a critical role in host amino acid metabolism, and dysbiosis in Crohns disease can significantly influence microbial production or consumption of key amino acids, including tryptophan, branched-chain amino acids, and those involved in sulfur metabolism