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When taking Semaglutide, you may experience some common side effects, including: Gastrointestinal Issues: Nausea, diarrhea, vomiting, constipation, and abdominal discomfort are frequent, especially when starting treatment or after a dose increase

People taking metformin for diabetes may have reduced B12 levels and should discuss monitoring with their GP

While the assumption of no intercurrent events is often not entirely realistic, this estimate is the closest we can currently get to an estimate of the true pharmacological effect of the drug and is referred to as the trial product estimate