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El-Beltagy et al

These weight reductions were associated with improvements in cardiometabolic risk factors and sustained effects over two years

Tirzepatide has been studied across a wide range of body weights (from 40 kg to over 200 kg), with only minor differences in exposure that are not clinically significant enough to warrant dose modifications

Since the current definition of ferroptosis is a cell death process involving lipid peroxidation that is suppressed by both iron chelators and lipophilic antioxidants, any lethal iron-dependent lipid peroxidation would be classified as ferroptosis