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Platelet intrinsic apoptosis relies on the mitochondrial apoptosome-mediated caspase-9/caspase-3-dependent mechanism, is tightly regulated by Bcl-XL, Bak, and Bax, and lacks the Fas receptor present on erythrocytes [499]

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At final model 3, as our study focused on DM population, DM-related variables including fasting glucose level, duration of DM, and insulin use were additionally adjusted compared to model 2

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Association of smoking and cardiometabolic parameters with albuminuria in people with type 2 diabetes mellitus: a systematic review and meta-analysis