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The copper-iron chronicles: the story of an intimate relationship

The pathogenesis of PCOS involves oxidative stress as a fundamental factor which disrupts follicular development while inducing granulosa cell apoptosis and promoting insulin resistance (1)

Frontiers in pharmacology , 16 , 1588284

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Proteomic analysis in animal models also showed the overexpression of plasma orosomucoid 2, and the sensitivity and specificity in using elevated orosomucoid 2 to discriminate cholangiocarcinoma cases from healthy controls were 92.9% (65 out of 70 cases) and 73.7% (350)