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Rushworth and Megson, 2014

Recent evidence has suggested that GPx1 and c-Src tyrosine kinases participate in the phosphorylation of IB which, in response to hypoxia, leads to the activation of NF-B elevated in hydrogen peroxide-treated embryonic fibroblasts [50]

Glutathione works by protect energy-producing factories inside cells called mitochondria. Antioxidants are molecules that inhibit other molecules from going through oxidation, a chemical reaction that produces toxins called free radicals

Specifically, the following aspects are described: (i) description of ROS and RNS and antioxidant defenses, (ii) the importance of reduced glutathione (GSH) as an antioxidant agent, (iii) the participation of GSH in the prevention of cardiovascular diseases, (iv) the relationship between the production of reactive species and the development of cardiovascular diseases

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