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Its part of the bodys innate defense systemplaying a critical role in maintaining the integrity of the gastrointestinal tract and promoting tissue repair throughout the body

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It was hypothesized that the acquisition of a procoagulant phenotype by medulloblastomafavors its dissemination because the enrichment of the tumor environment with fibrin protects the cancer cells from the immune system and forms a matrix for cell migration (Provencal et al., 2009)