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Hemolytic jaundice is due to excess unconjugated or free bilirubin (also called indirect), so, even when it is very intense, it is never accompanied by choluria (acholuric jaundice) and pruritus, except when it coexists with a hepatobiliary disease (lithiasis and bile duct obstruction)

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doi: 10.1016/j.bpc.2020.106524 55 YamamotoSDeckterLAKasaiKChioccaEASaekiY

Mar 2017

For certain treatments, the full effects may become more noticeable within a few hours or by the next day.