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Carnitines increase plasma levels of adenosine and ATP in humans Vasc Med 1997

Sundheim G., Bengtsson-Olivecrona G., 1987b

Writingreview and editing, RZ, YJ, PJ, KW, LSX, YS

24 , S26S39 (2019)

Carnitine synthesis requires gamma-butyl betaine hydroxylase, and premature infants have a limited capacity to synthesize L-carnitine themselves, having only 1215% of the synthesis ability of adults ( 3.2 L-carnitine levels in preterm infants Due to the large transfer of maternal L-carnitine to the fetus in the third trimester and the immature mechanism of carnitine transport in premature infants, the blood level of l-carnitine in premature infants after 3 to 7 days is slightly higher than that in full-term infants ( Consequently, despite the potential for higher initial blood levels, the inherent physiological immaturity and reduced somatic mass associated with preterm birth mean that these infants have significantly diminished endogenous L-carnitine reserves