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Description

Molecular interactions in the insulin-like growth factor (IGF) axis: a surface plasmon resonance (SPR) based biosensor study

doi: 10.3201/eid2204.151302 43 WilsonHWAmo-AddaeMKenuEIlesanmiOSAmemeDKSackeySO

Molecules 30:1888

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N-acetylcysteine shows dose-dependent inhibition of SARS-CoV-245-47, shows anti-inflammatory and immunomodulatory effects against SARS-CoV-2-induced immune responses in combination with bromelain48, suppressed virus-induced reactive oxygen species and blocked viral replication in a humanized mouse model and in human lung cells49, may limit COVID-19 induced cardiac damage by boosting cellular antioxidant defenses and potentially mitigating the oxidative stress caused by spike protein-induced ROS production in cardiac fibroblasts22, and reduces disulfide bonds in proteins and exhibits antioxidant properties that may inhibit viral replication and modulate inflammatory responses50