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Hertenstein): Nothing to disclose P581 Pneumocystis jirovecii prophylaxis: From guidelines to real life Rabah Redjoul 1 , Christine Robin 2,3 , Francoise Foulet 4 , Mathieu Leclerc 3,5 , Florence Beckerich 5 , Ludovic Cabanne 5 , Roberta di Blasi 5 , Cecile Pautas 5 , Andrea Toma 5 , Sebastien Maury 3,5 , Francoise Botterel 3,4 , Catherine Cordonnier 3,6 1 2,3 4 3,5 5 5 5 5 5 3,5 3,4 3,6 1 Henri Mondor Hospital-Assistance Publique Hopitaux de Paris (AP-HP), Hematology, Crteil, France

Excessive UV exposure: Sunlight is healthy, but overexposure creates free radicals in the skin

A lower ratio may suggest increased oxidative burden, chronic inflammation, or poor detoxification capacity

This is not a potency loss scenario

This recontextualized ipamorelin from a GHRP-like agonist to a ghrelin mimetic and opened research directions in gastrointestinal motility, appetite, and energy homeostasis beyond the pituitary axis