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Metabolic preference reflects both intrinsic genetic and epigenetic alterations in tumor cells 266 and extrinsic cues such as nutrient availability, oxygen levels, and signaling molecules from the surrounding niche 267,268 (Fig

doi: 10.1086/323264 23 CookE

10.1016/j.mehy.2020.109638 103 World Health Organization (2024)

mitigating joint bone erosion and autoantibody production in RA

Studies have found IL-13 activates the mTOR signaling pathway and downregulates miR-143, followed by the downregulation of epidermal barrier related proteins