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These observations allowed postulating that intracellular redox state of the thiol pool, which strongly depends on GSH level, can drive autophagic response at multiple levels ( Figure 2 )

Plasmid construction and transfections For over-expression and lentiviral packaging, pCMV-KCNN3-3*Flag, pCMV-Vector, PMD2G, and PSPAX2 were purchased from MiaoLing plasmid platform

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Claus, S

In a randomized, blinded, placebo-controlled clinical trial, the effects of ALA supplementation on spermatogram and seminal oxidative stress biomarkers in infertile men were studied [105]