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These findings clearly show that ALA could significantly inhibit the ER stress induced by CSD, and subsequently decreases the development of metabolic dysfunction through diminishing the caspase 3-mediated apoptotic signaling

287 , E97E104 (2004)

Ng 2002 Preclinical data in obese Zucker rats confirmed that 500 mcg/kg/day by intraperitoneal injection for 18 days preserved insulin sensitivity, unlike intact hGH