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This study pioneered an in vivo self-assembly strategy to develop a PKM2 allosteric converter, dually suppressing the Warburg effect and chemoresistance in renal cell carcinoma (RCC) through an enzyme-responsive self-assembly and sustained activation mechanism

Second Nature has worked with the NHS for over 6 years providing weight-loss programmes across the UK

Here, we examined whether and how oxidative stress induces ferroptosis in cardiomyocytes

However, clinical translation still faces challenges, such as administration routes, dosage optimization, and toxicity assessment, which require further investigation

Another eastern immigrant was John C