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Instead, studies have shown that the application of GSH or ferrostatin-1 can promote the reversal of ferroptosis, possibly because GSH enhances the GPX4 activity to arrest ROS accumulation (29), while ferrostatin-1 is a ROS scavenger that can remove the excessive cytosolic and lipid ROS (30)

Amorphizing metal selenides-based ROS biocatalysts at surface nanolayer toward ultrafast inflammatory diabetic wound healing

CreedonACBernardHAmatiFSegataNWallaceMArrAet al

It should be considered in adults with unusual clinical features or those not responding to standard treatments

8G), suggesting that hormetic responses are activated under these conditions