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Reported results have shown that the addition of pharmacological ascorbate to platinum-based chemotherapy significantly improves tumor deterioration in the advanced stage of NSCLC, by meeting its primary endpoint with an objective response rate of 34.2% and reaching a disease-control rate of 84.2%

Neuroscience 427 , 4357

However, for these treatment modalities there remain patients that do not respond or ultimately relapse

Amino acid losses during hemodialysis with polyacrylonitrile membranes: effect of intradialytic amino acid supplementation on plasma amino acid concentrations and nutritional variables in nondiabetic patients