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The key steps include: 1) Formation of Acyl-CoA : Fatty acids are activated in the cytosol by combining with Coenzyme A (CoA), forming acyl-CoA

Subsequently, repair or degeneration occur, which depend on multiple factors such as the type and extent of damage, the immune system, the genetic susceptibility to disc degeneration, which is linked with age, the biomechanical (functional) condition that is created by the injury, and finally the type of treatment: conservative (disc loading) or operative (disc unloading)

When it comes to standards, we dont launch our products until we meet the industrial standards and requirements of researchers

Given the significant role of the brain tumor microenvironment in radiation response (Table 3), this would represent a key advancement upon current models

Int J Mol Sci 2020;21:868