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[] A phase 3 double-blind, placebo and randomized controlled clinical trial, which studied the long-term effect of OCA in PBC patients, who did not tolerate or respond to UDCA therapy, revealed that OCA improved liver fibrosis and biliary injury in PBC patients after three years of treatment

Wojakowska A, Cole LM, Chekan M, Bednarczyk K, Maksymiak M, Oczko-Wojciechowska M, et al

*Correspondence: Haifeng Wang [email protected] This article was submitted to Nutrition and Metabolism, a section of the journal Frontiers in Nutrition Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Among these, the relative concentrations of 62 metabolites were significantly influenced by either GDH2 or GDH3 gene deletions (Fig

A standalone B-complex tablet wont reliably correct or prevent the deficiency the protocol is designed to head off