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doi: 10.1016/j.plaphy.2011.05.004 36 DietzK

FIGURE 7 Discussion We show here that modulating cell redox status by manipulating GSH metabolism primarily affects the IP 3 /Ca 2+ pathway in C6 astroglioma cell line (see scheme in Figure 8)

Oxidative stress (OS), defined as a redox imbalance that favors oxidative load, is commonly observed in cancer cells and is increasingly recognized as a hallmark of various cancers (Harris and DeNicola, 2020

This interaction between bile acids and TGR5 reduces NLRP3 inflammasome activation, inhibits NF-B signaling, and induces IL-10 production via CREB [208]

A study exploring the response of Atgstu19 and Atgstu24 mutants to TuMV infection showed significant differences in specific AtGSTU gene expression, virus concentration, ultrastructural alterations, glutathione content, and glutathione transferase and reductase activities compared with Col-0 (wild-type) and mock-inoculated plants ( Atgstu24 mutants had a resistance-like reaction to TuMV (with a high decrease in virus gene expression and movement) compared to susceptible Col-0 plants, suggesting that GSTU24 may suppress plant resistance