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[18,19] While a rigorous characterization of senescent cells in vitro can generally be obtained by multiplexing three or more of these consensual markers, quantification of senescence in vivo is often complicated by the fact that tissue homogenates are composed of varied cell types and expression levels, among which senescent cells account for a relatively small percentage

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AAV-PHP.eB-EF1a-GFP was packaged by the Viral Vector Core in the Department of Neuroscience and Regenerative Medicine at Augusta University

1 2 "Molecular basis of glutathione reductase deficiency in human blood cells"

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