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After the interruption of carcinogen administration to rats, the development of HCCs is associated with a decrease in SAM content and SAM/SAH ratio in dysplastic nodules (DN) and HCC [5]

PMID 10875602

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32,65 Excretion of excess copper occurs primarily through the following pathways: (I) metabolized copper in the liver is incorporated into bile and subsequently excreted from the body in the form of secretory vesicles, which represents the primary mechanism for endogenous copper elimination