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345.Ceriello A, Novials A, Ortega E, Canivell S, La Sala L, Pujadas G, Bucciarelli L, Rondinelli M, Genovese S

However, glutamine is a major driver for OXPHOS in cancer cells, and glutamine limitation, rather than glucose contributes to lower oxygen uptake and mediates the apoptosis of cancer cells ( The rate-limiting mitochondrial enzyme in glutamine metabolism is glutaminase, which catalyzes the conversion of glutamine into glutamate and ammonia