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Your immune system is so suppressed from the rituximab that the vaccine wont be effective. While her rheumatologist could not cite data specific to rituximab and the COVID-19 vaccine, she was basing her advice based on whats known about how people on rituximab respond to other vaccines, such as flu, as well as whats known about how rituximab affects the immune system, especially compared to other kinds of biologics

If a medication sharply lowers a patients number of white blood cells, doctors might reduce the dose

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As the association grew, we upgraded to a garage, then a rented office next to the Katella facility, and on to an office near Santa Anas Civic Center

10.1084/jem.20140857 158 McLaughlinR