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Clinical trials have established the proof-of-concept for intrathecal ASO therapy, exemplified by tofersen for SOD1-ALS, which achieved accelerated approval based on biomarker reduction despite not meeting the primary clinical endpoint in its phase 3 VALOR trial (8, 43, 44)
Despite its critical role in research, many people are confused about what it is, how it differs from regular sterile water, and when to use each
Regular use visibly brightens your complexion, giving you smooth, radiant skin with a more balanced, even skin tone
