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Figure 6 Our observations implied that MAPKAPK2 was associated with reduced KEAP1 levels and enhanced Nrf2 nuclear localization, concomitant with increased HO-1 expression, suggesting a potential role in reinforcing antioxidant defenses in vitiligo melanocytes

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Only 13 (13/82, 15.9%) studies were RCTs recruiting for 100 or more participants (Table 3), involving digital therapeutics, multidisciplinary surgery, and collaborations with psychotherapists, physiotherapists, nutritionists, primary care practitioners as well as biochemistry scientists

Marshall-Gradisnik S, Johnston S, Chacko A, Nguyen T, Smith P, Staines D