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This increase leads to an elevated conversion of tryptophan into kynurenine, a notable reduction in the production of indole-type metabolites, and an exacerbation of atherosclerosis (142)

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However, the metabolic crosstalk between cancer cells and CAFs is still unclear and needs to be further explored

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These findings suggest that declining acyl-carnitine levels may be linked to the onset and progression of Alzheimers, potentially serving as biomarkers for early detection and intervention