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Senescence was induced with 100 nM 4-OHT for 7 days, while non-senescent cell controls were obtained by treating cells with DMSO

[DOI] [PMC free article] [PubMed] [Google Scholar] Cabrera LY, Young Han C, Ostendorf T, Jimenez-Shahed J, Sarva H

H.CarverL

Research comparing time-of-day administration for autophagy inducers shows consistent 2535% reductions in target engagement when dosed during circadian autophagy suppression windows