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these findings are modeldependent and primarily preclinical (see Key references)

Elevation of Intracholedochal Pressure: Buprenorphine has been shown to increase intracholedochal pressure, as do other opioids, and thus should be administered with caution to patients with dysfunction of the biliary tract

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Pilot study of the effect of methyl B12 treatment on behavioral and biomarker measures in children with autism

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