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The peptides share structural similarities (both feature the Pro-Gly-Pro tail) and complementary mechanisms that suggest designed synergy

Design and synthesis of novel 3-(benzo[d]oxazol-2-yl)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine derivatives as selective G-protein-coupled receptor kinase-2 and -5 inhibitors

doi: 10.3389/fnut.2026.1676497 Received 30 July 2025 Revised 18 December 2025 Accepted 05 January 2026 Published 13 February 2026 Volume 13 - 2026 Edited by Senthil Kumaran Satyanarayanan, Hong Kong Institute of Innovation and Technology, Hong Kong SAR, China Reviewed by Luciene Bruno Vieira, Federal University of Minas Gerais, Brazil Iffet Ipek Bosgelmez, Erciyes University, Trkiye Updates Copyright 2026 Miteva, Laurenti, Mattioli, Di Risola, Mariano and Mosca

Results may vary

It is available in both delayed release tablets that release the medication in the intestines for a delayed effect and extended release tablets, for consumption