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Its primary function is in tissue repair: it promotes actin polymerization (required for cell movement), upregulates anti-inflammatory proteins, and stimulates the migration of keratinocytes and endothelial cells that are needed to close and repair damaged tissue

[PubMed] [Google Scholar] [84].Hermanson G, Bioconjugate techniques, 1st ed, Academic Press, San Diego, CA, 1996

Basic fibroblast growth factor (bFGF) is essential in OPC in vitro expansion, as it promotes proliferation and blocks differentiation (Supplementary Fig