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Risks and Side Effects While generally safe, vitamin B12 injections can have side effects or risks, such as: Mild pain, swelling, or redness at the injection site Dizziness, headache, or nausea Allergic reactions (rare) Hypokalemia (low potassium levels) in individuals with severe deficiency undergoing treatment People with allergies to cobalt or who have Lebers disease should avoid B12 injections unless specifically advised by a doctor

alcohol-producing bacteria (e.g., Klebsiella pneumoniae ) increase the level of endogenous ethanol, disrupting mitochondrial integrity and accelerating MAFLD

Athletes or those who struggle with fatigue

[DOI] [PMC free article] [PubMed] [Google Scholar] 45.Amory JK, Wang C, Swerdloff RS, Anawalt BD, Matsumoto AM, Bremner WJ, Walker SE, Haberer LJ, Clark RV