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Description

In conditions of mechanical stress, inflammation, oxidative stress, and hypoxia, 16-OHE reduces PPAR levels, thus relieving the inhibitory effect on Smad3 and enhancing TGF--Smad 2/3-Smad4 signaling, thereby promoting EndoMT [54, 56]

2018DG008)

Environmental pollutants, UV rays, and even internal stress create free radicalsunstable molecules that damage cells

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