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Once you hit the 6-month period, or 6 total refills, take a break from B12/MIC for a minimum of 3 months

Adults over 50, vegetarians and vegans, and people with gastrointestinal issues may need to take vitamin B12 supplements to avoid deficiency

Red cell or serum folate

AHK-Cu (Ala-His-Lys copper complex) engages copper-dependent signaling pathways, acting as a copper-binding tripeptide that modulates extracellular matrix remodeling enzyme activity

Supplements and Down syndrome There are mixed data regarding whether people with Down syndrome require the active forms (versus inactive forms) of vitamin B12 and folate when taking a supplement