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Retatrutide is an investigational GLP-1, GIP, and glucagon triple receptor agonist currently in Phase 3 trials

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[1] Initial development of this peptide appears to be based on research suggesting that the lipolytic activity of hGH is largely mediated by its C-terminal domain, independently of its growth-promoting implications

Critically, two of the efficacy studies were long-term investigations extending up to 24 weeks, providing meaningful data on sustained exposure safety

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