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Once inside the cell, the sulfhydryl (-SH) group of the glutathione molecule acts as a potent reducing agent, directly donating an electron to unstable reactive oxygen species

In mammals, this multitasking indolamine is synthesized in the pineal gland in a circadian manner in response to the photoperiodic information received via the retinohypothalamic pathway 4,5

Ascorbate oxidase (AO) is a glycoprotein and a member of blue copper oxidase family that mediates ascorbate oxidation to dehydroascorbate (DHA) which usually follows high affinity transport across the membrane (Smirnoff, 2000