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Elevated PTEN levels, on the other hand, diminish glucose uptake while promoting mitochondrial biogenesis and multidrug resistance

Nat Cell Biol 9:654659 van den Berg RA, Hoefsloot HCJ, Westerhuis JA, Smilde AK, van der Werf MJ (2006) Centering, scaling, and transformations: improving the biological information content of metabolomics data

Molecular cloning and expression of human liver bile acid CoA:amino acid N-acyltransferase.26930(July 1994),1937519379,0021-9258 29

The higher the energy needs (higher metabolism, exercise, stress, etc.), the harder the mitochondria have to work and the more free radicals they produce

This makes it particularly susceptible to oxidative stress