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3 The L-NAME Interaction: A Mechanistic Proof of Concept The L-NAME experimental paradigm deserves specific attention because it constitutes the clearest mechanistic evidence for NO pathway dependency

reported that both glutathione forms, GSH and GSSG, may improve skin elasticity in either sun-exposed or sun-protected areas

Used in explaining increased frequency of seizures in epilepsy and progression of bipolar disorder in humans. Jason et al have recently (2011) proposed kindling as an etiological model for ME/CFS : Kindling might represent a heuristic model for understanding the etiology of Myalgic Encephalomyelitis/chronic fatigue syndrome (ME/CFS)

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They did not show narrowing of the blood vessel lumen